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高崎量子応用研究所

プロジェクト「RI医療応用研究」の業績一覧

掲載日:2019年6月7日更新
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業績一覧

原著論文

2019

Anti-tumor Effects and Potential Therapeutic Response Biomarkers in α-Emitting meta-211At-Astato-Benzylguanidine Therapy for Malignant Pheochromocytoma Explored by RNA-sequencing, Ohshima Y, Kono N, Yokota Y, Watanabe S, Sasaki I, Ishioka NS, Sakashita T, Arakawa K, Theranostics, 2019;9(6):1538-1549. [DOI: 10.7150/thno.30353]

A convenient and reproducible method for the synthesis of astatinated 4-[211At]astato-L-phenylalanine via electrophilic desilylationS. Watanabe, M. Anwar-Ul Azim, I. Nishinaka, I. Sasaki, Y. Ohshima, K. Yamada, N. S. Ishioka, Org Biomol Chem, 2019;17:165-171. [DOI: 10.1039/C8OB02394H]

2018

Rational evaluation of the therapeutic effect and dosimetry of auger electrons for radionuclide therapy in a cell culture model, Shinohara A, Hanaoka H, Sakashita T, Sato T, Yamaguchi A, Ishioka NS, Tsushima Y., Ann Nucl Med. 2018;32(2):114-122. [DOI: 10.1007/s12149-017-1225-9]

Antitumor effects of radionuclide treatment using α-emitting meta-211At-astato-benzylguanidine in a PC12 pheochromocytoma model, Ohshima Y, Sudo H, Watanabe S, Nagatsu K, Tsuji AB, Sakashita T, Ito YM, Yoshinaga K, Higashi T, Ishioka NS., Eur J Nucl Med Mol Imaging. 2018;45(6):999-1010. [DOI: 10.1007/s00259-017-3919-6]

Improvement and Optimization of Clinically Potent Positron Emitter 76Br Isolation Using the Dry Distillation Approach for its Future Automation, S. Watanabe, A. Shimada, S. Watanabe, H. Hanaoka, Noriko S. Ishioka, Trans. Mat. Res. Soc. Japan, 2018;43(4):219-222. [DOI: 10.14723/tmrsj.43.219]

Thin layer chromatography for astatine and iodine in solutions prepared by dry distillation, I. Nishinaka, K. Hashimoto, H. Suzuki, Journal of Radioanalytical and Nuclear Chemistry, 2018;318(2):897-905 [DOI: 10.1007/s10967-018-6088-6]

2017

Production of iodine radionuclides using 7Li ion beams, I. Nishinaka, A. Yokoyama, K. Washiyama, H. Makii, and K. Hashimoto, Journal of Radioanalytical and Nuclear Chemistry, 2017;314(3):1947–1965. [DOI: 10.1007/s10967-017-5525-2]

Role of Multichance Fission in the Description of Fission-Fragment Mass Distributions at High Energies, Hirose K, Nishio K, Tanaka S, Léguillon R, Makii H, Nishinaka I, Orlandi R, Tsukada K, Smallcombe J, Vermeulen MJ, Chiba S, Aritomo Y, Ohtsuki T, Nakano K, Araki S, Watanabe Y, Tatsuzawa R, Takaki N, Tamura N, Goto S, Tsekhanovich I, Andreyev AN, Phys Rev Lett. 2017;119(22):222501. [DOI:10.1103/PhysRevLett.119.222501]

The 95Zr(n, γ)96Zr Cross Section from the Surrogate Ratio Method and Its Effect on s-process Nucleosynthesis, S. Q. Yan, Z. H. Li, Y. B. Wang , K. Nishio, M. Lugaro, A. I. Karakas, H. Makii, P. Mohr, J. Su, Y. J. Li, I. Nishinaka, K. Hirose, Y. L. Han, R. Orlandi, Y. P. Shen, B. Guo , S. Zeng, G. Lian, Y. S. Chen, and W. P. Liu, The Astrophysical Journal, 2017;848(2) 98-1-8. [DOI: 10.3847/1538-4357/aa8c74]

2016

Efficacy of system L amino acid transporter 1 inhibition as a therapeutic target in esophageal squamous cell carcinoma, Yasuhiro Ohshima, Kyoichi Kaira, Aiko Yamaguchi, Noboru Oriuchi, Hideyuki Tominaga, Shushi Nagamori, Yoshikatsu Kanai, Takehiko Yokobori,Tatsuya Miyazaki, Takayuki Asao, Yoshito Tsushima, Hiroyuki Kuwano and Noriko S. Ishioka, Cancer Science (Acceptedmanuscript online: 28 July 2016) [DOI: 10.1111/cas.13021]

Medical application of radiohalogenated peptides:synthesis and in vitro evaluation of F(p-131I)KCCYSL for targeting HER2 in vitro, I. Sasaki, S. Watanabe, Y. Ohshima, Y. Sugo, K. Yamada, H. Hanaoka, andN. S. Ishioka, Peptide Science 2015, 243-246 (2016)

Simultaneous analysis of silicon and boron dissolved in water bycombination of electrodialytic salt removal and ion-exclusionchromatography with corona charged aerosol detection, M. Mori, K. Sagara, K. Arai, N. Nakatani, S. Ohira, K. Toda, H.Itabashi, D. Kozaki, Y. Sugo, Sh. Watanabe, N. S. Ishioka and K. Tanaka, J. ChromatographyA 1431, 131-137 (2016) [DOI: 10.1016/j.chroma.2015.12.064]

2015

Preparation and evaluation of an astatine-211-labeled sigma receptor ligand for alpha radionuclidetherapy, K. Ogawa, Y. Mizuno, K. Washiyama, K. Shiba, N. Takahashi, T. Kozaka,Sh. Watanabe, A. Shinohara, A. Odani, Nucl. Med. Biol. 42, 875-879 (2015) [DOI: 10.1016/j.nucmedbio.2015.07.001]

Extraction of astatine isotopes for development of radiopharmaceuticalsusing a 211Rn-211At generator, E. Maeda, A. Yokoyama, T. Taniguchi, K. Washiyama, I. Nishinaka, J. Radioanal. Nucl. Chem. 303, 1465-1468 (2015) [DOI: 10.1007/s10967-014-3586-z]

Development of a widely usable amino acid tracer : 76Br-α-methyl-phenylalanine for tumor PET Imaging, H. Hanaoka, Y.Ohshima, Y. Suzuki, A. Yamaguchi, Sh. Watanabe, T. Uehara, S. Nagamori,Y. Kanai, N. S. Ishioka, Y. Tsushima, K. Endo and Y. Arano, J Nucl.Med., 56(5), 791-797 (2015) [DOI: 10.2967/jnumed.114.152215]

In vitro studies on cellular binding and stability of 64Cu-labeledpeptide for tumor imaging, Y. Sugo, Y. Ohshima, I. Sasaki and N. S.Ishioka, Peptide Science 2014, 303-306 (2015).

Exploring of peptides with affinity to HER2 from random peptidelibraries using radioisotope; Random hexapeptide libraries with fixedamino acid sequence at 1 and 2 positions, I. Sasaki, H. Hanaoka, K.Yamada, Sh. Watanabe, Y. Sugo, Y. Ohshima, H. Suzuki and N. S. Ishioka, Peptide Science 2014, 257-260 (2015).

Production and separation of astatine isotopes in the 7Li + natPb reaction. I. Nishinaka, A. Yokoyama, K. Washiyama, E. Maeda, S. Watanabe, K. Hashimoto, N. S. Ishioka, H. Makii, A. Toyoshima, N. Yamada, R. Amano, J. Radioanal. Nucl. Chem. (2015 in press) [DOI: 10.1007/s10967-015-3975-y]

α-Radiation Effect on Solvent Extraction of Minor Actinide. Y. Sugo, Y. Sasaki, M. Taguchi, N. S. Ishioka, J. Radioanal. Nucl. Chem., 303, 1381-1384 (2015) [DOI: 10.1007/s10967-014-3494-2]

Lutetium-177 complexation of DOTA and DTPA in the presence of competing metals. S. Watanabe, K. Hashimoto, N.S. Ishioka, J. Radioanal. Nucl. Chem. 303, 1519-1521 (2015) [DOI: 10.1007/s10967-014-3590-3]

Production of highly purified no-carrier-added 177Lu for radioimmunotherapy. Satoshi Watanabe, Kazuyuki Hashimoto, Shigeki Watanabe, Yasuhiko Iida, Hirofumi Hanaoka, Keigo Endo, Noriko S. Ishioka, J. Radioanal. Nucl. Chem., 303, 935-940 (2015) [DOI: 10.1007/s10967-014-3534-y]

2014

Prognostic significance of amino-acid transporter expression (LAT1,ASCT2, and xCT) in surgically resected tongue cancer. M. Toyoda, K.Kaira, Y. Ohshima, N. S. Ishioka, M. Shino, K. Sakakura, Y. Takayasu, K.Takahashi, H. Tominaga, N. Oriuchi, S. Nagamori, Y. Kanai, T. Oyama andK. Chikamatsu, Br. J. Cancer, 110, 2506-2513 (2014) [DOI: 10.1038/bjc.2014.178]

First Measurement of the Radionuclide Purity of the Therapeutic Isotope 67Cu Produced by 68Zn(n,x) Reaction Using natC(d,n) Neutrons. Nozomi Sato, Kazuaki Tsukada, Satoshi Watanabe, Noriko S. Ishioka, Masako Kawabata, Hideya Saeki, Yasuki Nagai, Tadahiro Kin, Futoshi, Minato, Nobuyuki Iwamoto, Osamu Iwamoto, J. Phys. Soc. Jpn. 83, 073201 (2014) [DOI: 10.7566/JPSJ.83.073201]

Prognostic significance of amino-acid transporter expression (LAT1, ASCT2, and xCT) in surgically resected tongue cancer. M. Toyoda, K. Kaira*, Y. Ohshima*, N.S. Ishioka, M. Shino, K. Sakakura, Y. Takayasu, K. Takahashi, H. Tominaga, N. Oriuchi, S. Nagamori, Y. Kanai, T. Oyama, K. Chikamatsu, Br. J. Cancer, 110, 2506-2513 (2014) [DOI: 10.1038/bjc.2014.178] * These authors equally contributed to this work.

Biological significance of fluorine-18-α-methyltyrosine (FAMT) uptake on PET in patients with oesophageal cancer. S. Suzuki*, K. Kaira*, Y. Ohshima*, N.S. Ishioka, M. Sohda, T. Yokobori, T. Miyazaki, N. Oriuchi, H. Tominaga, Y. Kanai, N. Tsukamoto, T. Asao, Y. Tsushima, T. Higuchi, T. Oyama, H. Kuwano, Br. J. Cancer, 110, 1985-1991 (2014) [DOI: 10.1038/bjc.2014.142] * These authors equally contributed to this work.

Synthesis and in vitro evaluation of 64Cu-labeled peptide for tumor imaging. Y. Sugo, I. Sasaki, S. Watanabe, Y. Ohshima, N.S. Ishioka, Peptide Science 2013, 355-358 (2014)

2013

Evaluation of a Wet Chemistry Method for Isolation of Cyclotron Produced [211At]Astatine. E. R. Balkin, D. K. Hamlin, K. Gagnon, M.-K. Chyan, S. Pal, S. Watanabe, D. S. Wilbur, Appl. Sci., 3, 636-655 (2013) [DOI:10.3390/app3030636]

Synthesis of radiohalogen-labeled peptides with high affinity to HER2/neu receptor. I. Sasaki, K. Yamada, S. Watanabe, H. Hanaoka, Y. Sugo, H. Oku, N.S. Ishioka, Peptide Science 2012, 157-160 (2013)

2012

Biological and evaluation of 3-[18F]fluoro-α-methyl-D-tyrosine (D-[18F]FAMT) as a novel amino acid tracer for positron emission tomography. Y. Ohshima, H. Hanaoka, H. Tominaga, Y. Kanai, K. Kaira, A. Yamaguchi, S. Nagamori, N. Oriuchi, Y. Tsushima, K. Endo, N.S. Ishioka, Ann. Nucl. Med., 27, 314-324, (2013) [DOI: 10.1007/s12149-013-0687-7]

Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer. K. Kaira, Y. Sunose*, Y. Ohshima*, N.S. Ishioka, K. Arakawa, T. Ogawa, N. Sunaga, K. Shimizu, H. Tominaga, N. Oriuchi, H. Itoh, S. Nagamori, Y. Kanai, A. Yamaguchi, A. Segawa, M. Ide, M. Mori, T. Oyama, I. Takeyoshi, BMC Cancer, 13, 482 (2013) [DOI: 10.1186/1471-2407-13-482] * These authors equally contributed to this work.

Synthesis and in vivo evaluation of radiohalogen-labeled antitumor cyclic peptides. K. Yamada, S. Watanabe, Y. Ohshima, H. Hanaoka, N. Tsukui, C. Takano, A. Yamaguchi, H. Oku, N.S. Ishioka, Peptide Science 2011, 287-290 (2012)

2011

Predicting cetuximab accumulation in KRAS wild-type and KRAS mutant colorectal cancer using 64Cu-labeled cetuximab positron emission tomography. A. Achmad, H. Hanaoka, H. Yoshioka, S. Yamamoto, H. Tominaga, T. Araki, Y. Ohshima, N. Oriuchi, K. Endo. Cancer Science [DOI: 10.1111/j.1349-7006.2011.02166.x]

Electron absorbed fractions and S values in a voxel-based mouse phantom, A. Mohammadi and S. Kinase, Radioisotopes 60, 505-512(2011). [DOI:10.3769/radioisotopes.60.505]

Influence of voxel size on specific absorbed fractions and S values in a mouse voxel phantom, A. Mohammadi and K. Kinase, Radiation Protection Dosimetry, 143(2-4), 258-263 (2011) [DOI: 10.1093/rpd/ncq391]

Preparation and biological evaluation of 3-[76Br]bromo-[alpha]-methyl-l-tyrosine, a novel tyrosine analog for positron emission tomography imaging of tumors. Y. Ohshima, H. Hanaoka, S. Watanabe, Y. Sugo, S. Watanabe, H. Tominaga, N. Oriuchi, K. Endo, N.S. Ishioka. Nucl. Med. Biol., 38, 857-865 (2011) [DOI: 10.1016/j.nucmedbio.2011.02.001 ]

Monte Carlo Simulations of Photon Specific Absorbed Fractions in a Mouse Voxel Phantom. A. Mohammadi and S. Kinase, Progress in NUCLEAR SCIENCE and TECHNOLOGY 1: 126-129, 2011

2010

PET imaging of norepinephrine transporter (NET)-expressing tumors using 76Br-meta-bromobenzylguanidine (76Br-MBBG). S. Watanabe, H. Hanaoka, J. X. Liang, Y. Iida, K. Endo, and N. S. Ishioka, Journal of Nuclear Medicine 51: 1472-1479, 2010 [DOI: 10.2967/jnumed.110.075465]

Imaging and biodistribution of Her2/neu expression in non-small cell lung cancer xenografts with 64Cu-labeled trastuzumab PET. P. Paudyal, B. Paudyal, H. Hanaoka, N. Oriuchi, Y. Iida, H. Yoshioka, H. Tominaga, S. Watanabe, S. Watanabe, N. S. Ishioka and K. Endo. Cancer Science 101: 1045-1050, 2010 [DOI: 10.1111/j.1349-7006.2009.01480.x]

Tracing cadmium from culture to spikelet: non-invasive imaging and quantitative characterization of absorption, transport and accumulation of cadmium in an intact rice plant, S. Fujimaki, N. Suzui, N.S. Ishioka, N. Kawachi, S. Ito, M. Chino, S. Nakamura. Plant Physiology 152: 1796-1806, 2010 [DOI: 10.1104/pp.109.151035]

S. Fujimaki, S. Ishii, N.S. Ishioka (2010) Non-invasive imaging and analyses of transport of nitrogen nutrition in intact plants using a positron-emitting tracer imaging system (PETIS). In: Ohyama T, Sueyoshi K (eds) Nitrogen Assimilation in Plants. Research Signpost, Kerala, India

11CO2と植物用ボジトロンイメージング装置を用いたダイズ植物の根粒に対する光合成産物移行のリアルタイム解析, 伊藤小百合, 鈴井伸郎, 河地有木, 石井里美, 石岡典子, 藤巻秀. Radioisotopes 59: 145-154, 2010

2009

Real-time imaging of nitrogen fixation in an intact soybean plant with nodules using 13N-labeled nitrogen gas. S. Ishii, N. Suzui, S. Ito, N. S. Ishioka, N. Kawachi, N. Ohtake, T. Ohyama and S. Fujimaki. Soil Science and Plant Nutrition 55: 660-666, 2009 [DOI: 10.1111/j.1747-0765.2009.00403.x]

Evaluation of 64Cu-labeled DOTA-D-Phe1-Tyr3-octreotide (64Cu-DOTA-TOC) for imaging somatostatin receptor-expressing tumors. H. Hanaoka, H. Tominaga, K. Yamada, P. Paudyal, Y. Iida, S. Watanabe, B. Paudyal, T. Higuchi, N. Oriuchi, and K. Endo Ann. Nucl. Med., 23: 559-567. 2009 [DOI: 10.1007/s12149-009-0274-0]

Chelating ion-exchange methods for the preparation of no-carrier-added 64Cu. S. Watanabe, S. Watanabe, J. X. Liang, H. Hanaoka, K. Endo, and N. S. Ishioka. Nuclear Medicine and Biology 36: 587-590, 2009 [DOI: 10.1016/j.nucmedbio.2009.04.005]

Production of no-carrier-added 64Cu and applications to molecular imaging by PET and PETIS as a biomedical tracer. S. Watanabe, Y. Iida, N. Suzui, T. Katabuchi, S. Ishii, N. Kawachi, H. Hanaoka, S. Watanabe, S. Matsuhashi, K. Endo, N. Ishioka. Journal of Radioanalytical and Nuclear Chemistry 280: 199-205, 2009 [DOI: 10.1007/s10967-008-7443-9]

52Fe translocation in barley as monitored by a positron-emitting tracer imaging system (PETIS): evidence for the direct translocation of Fe from roots to young leaves via phloem. T. Tsukamoto, H. Nakanishi, H. Uchida, S. Watanabe, S. Matsuhashi, S. Mori, N. K. Nishizawa. Plant Cell Physiol 50: 48-57, 2009 [DOI: 10.1093/pcp/pcn192]

2008

Deoxymugineic acid increases Zn translocation in Zn-deficient rice plants. M. Suzuki, T. Tsukamoto, H. Inoue, S. Watanabe, S. Matsuhashi, M. Takahashi, H. Nakanishi, S. Mori, N. K. Nishizawa. Plant Molecular Biology 66: 609-617, 2008 [DOI: 10.1007/s11103-008-9292-x]

Analysis of NO3 interception of the parasitic angiosperm Orobanche spp. using a positron-emitting tracer imaging system and 13NO3-: A new method for the visualization and quantitative analysis of the NO3 interception ratio. N. Kawachi, S. Fujimaki, K. Sakamoto, N. S. Ishioka, S. Matsuhashi, H. Sekimoto. Soil Science and Plant Nutrition 54: 408-416, 2008 [DOI:10.1111/j.1747-0765.2008.00252.x]

Production of 67Cu via the 68Zn(p,2p)67Cu reaction and recovery of 68Zn target. T. Katabuchi, S. Watanabe, N. Ishioka, Y. Iida, H. Hanaoka, K. Endo, S. Matsuhashi. Journal of Radioanalytical and Nuclear Chemistry 277: 467-470, 2008 [DOI: 10.1007/s10967-007-7144-9]

2007

Production of endohedral 133Xe-higher fullerenes by ion implantation. S. Watanabe, T. Katabuchi, N. S. Ishioka, S. Matsuhashi, H. Muramatsu. Journal of Radioanalytical and Nuclear Chemistry 272: 467-469, 2007 [DOI: 10.1007/s10967-007-0605-3]

Synthesis of Endohedral 133Xe-Fullerenol by Using Higher Fullerene. S. Watanabe, T. Katabuchi, N. S. Ishioka, S. Matsuhashi. Journal of Nuclear and Radiochemical Sciences 8: 105-107, 2007

Mutational reconstructed ferric chelate reductase confers enhanced tolerance in rice to iron deficiency in calcareous soil. Y. Ishimaru, S. Kim, T. Tsukamoto, H. Oki, T. Kobayashi, S. Watanabe, S. Matsuhashi, M. Takahashi, H. Nakanishi, S. Mori, N. K. Nishizawa. Proceedings of the National Academy of Sciences of the United States of America 104: 7373-7378, 2007 [DOI: 10.1073/pnas.0610555104]

2006

52Mn translocation in barley monitored using a positron-emitting tracer imaging system. T. Tsukamoto, H. Nakanishi, S. Kiyomiya, S. Watanabe, S. Matsuhashi, N. K. Nishizawa, S. Mori. Soil Science and Plant Nutrition 52: 717-725, 2006 [DOI: 10.1111/j.1747-0765.2006.00096.x]

Biosynthesis and secretion of mugineic acid family phytosiderophores in zinc-deficient barley. M. Suzuki, M. Takahashi, T. Tsukamoto, S. Watanabe, S. Matsuhashi, J. Yazaki, N. Kishimoto, S. Kikuchi, H. Nakanishi, S. Mori, N. K. Nishizawa. Plant Journal 48: 85-97, 2006 [DOI: 10.1111/j.1365-313X.2006.02853.x]

A new visualization technique for the study of the accumulation of photoassimilates in wheat grains using 11CO2. S. Matsuhashi, S. Fujimaki, H. Uchida, N. S. Ishioka, T. Kume. Applied Radiation and Isotopes 64: 435-440, 2006 [DOI: 10.1016/j.apradiso.2005.08.020]

Kinetic analysis of carbon-11-labeled carbon dioxide for studying photosynthesis in a leaf using positron emitting tracer imaging system. N. Kawachi, K. Sakamoto, S. Ishii, S. Fujimaki, N. Suzui, N. S. Ishioka, S. Matsuhashi. Ieee Transactions on Nuclear Science 53: 2991-2997, 2006 [DOI: 10.1109/TNS.2006.881063]

Rice plants take up iron as an Fe3+-phytosiderophore and as Fe2+. Y. Ishimaru, M. Suzuki, T. Tsukamoto, K. Suzuki, M. Nakazono, T. Kobayashi, Y. Wada, S. Watanabe, S. Matsuhashi, M. Takahashi, H. Nakanishi, S. Mori, N. K. Nishizawa. Plant Journal 45: 335-346, 2006 [DOI: 10.1111/j.1365-313X.2005.02624.x]

2005

Conversion of endohedral 133Xe-fullerene to endohedral 133Xe-fullerenol to be used in nuclear medicine. S. Watanabe, N. S. Ishioka, T. Sekine, H. Kudo, H. Shimomura, H. Muramatsu, T. Kume. Journal of Radioanalytical and Nuclear Chemistry 266: 499-502, 2005 [DOI: 10.1007/s10967-005-0938-8]

Quantitative modeling of photoassimilate flow in an intact plant using the Positron Emitting Tracer Imaging System (PETIS). S. Matsuhashi, S. Fujimaki, N. Kawachi, K. Sakamoto, N. S. Ishioka, T. Kume. Soil Science and Plant Nutrition 51: 417-423, 2005 [DOI: 10.1111/j.1747-0765.2005.tb00047.x]

Input-output analysis of in vivo photoassimilate translocation using Positron-Emitting Tracer Imaging System (PETIS) data. A. J. Keutgen, N. Keutgen, S. Matsuhashi, C. Mizuniwa, T. Ito, T. Fujimura, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, H. Uchida, A. Tsuji, S. Hashimoto. Journal of Experimental Botany 56: 1419-1425, 2005 [DOI: 10.1093/jxb/eri143]

2003

Dose dependence of the production yield of endohedral 133Xe-fullerene by ion implantation. S. Watanabe, N. S. Ishioka, H. Shimomura, H. Muramatsu, T. Sekine. Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms 206: 399-402, 2003

Production of endohedral 133Xe-fullerene by ion implantation. S. Watanabe, N. S. Ishioka, T. Sekine, A. Osa, M. Koizumi, H. Shimomura, K. Yoshikawa, H. Muramatsu. Journal of Radioanalytical and Nuclear Chemistry 255: 495-498, 2003

Quick and reversible inhibition of soybean root nodule growth by nitrate involves a decrease in sucrose supply to nodules. H. Fujikake, A. Yamazaki, N. Ohtake, K. Sueyoshi, S. Matsuhashi, T. Ito, C. Mizuniwa, T. Kume, S. Hashimoto, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, H. Uchida, A. Tsuji, T. Ohyama. Journal of Experimental Botany 54: 1379-1388, 2003

2002

Transfer function analysis of positron-emitting tracer imaging system (PETIS) data. N. Keutgen, S. Matsuhashi, C. Mizuniwa, T. Ito, T. Fujimura, N. S. Ishioka, S. Watanabe, T. Sekine, H. Uchida, S. Hashimoto. Applied Radiation and Isotopes 57: 225-233, 2002

Effects of anion channel blockers on xylem nitrate transport in barley seedlings. T. Kawachi, C. Nishijo, H. Fujikake, S. Abdel-Latif, N. Ohtake, K. Sueyoshi, T. Ohyama, N. Shigeta-Ishioka, S. Watanabe, A. Osa, T. Sekine, S. Matsuhashi, T. Ito, C. Mizuniwa, T. Kume, S. Hashimoto, H. Uchida, A. Tsuji. Soil Science and Plant Nutrition 48: 271-277, 2002

2001

Effect of radiation-degraded chitosan on plants stressed with vanadium. L. Xuan Tham, N. Nagasawa, S. Matsuhashi, N. S. Ishioka, T. Ito, T. Kume. Radiation Physics and Chemistry 61: 171-175, 2001

Production of positron emitters of metallic elements to study plant uptake and distribution. S. Watanabe, N. S. Ishioka, A. Ose, M. Koizumi, T. Sekine, S. Kiyomiya, H. Nakanishi, S. Mori. Radiochimica Acta 89: 853-858, 2001

Rapid N transport to pods and seeds in N-deficient soybean plants. N. Ohtake, T. Sato, H. Fujikake, K. Sueyoshi, T. Ohyama, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, S. Matsuhashi, T. Ito, C. Mizuniwa, T. Kume, S. Hashimoto, H. Uchida, A. Tsuji. Journal of Experimental Botany 52: 277-283, 2001

18F used as tracer to study water uptake and transport imaging of a cowpea plant. T. M. Nakanishi, K. Tanoi, H. Yokota, D. J. Kang, R. Ishii, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, S. Matsuhashi, T. Ito, T. Kume, H. Uchida, A. Tsuji. Journal of Radioanalytical and Nuclear Chemistry 249: 503-507, 2001

Real time visualization of 13N-translocation in rice under different environmental conditions using positron emitting tracer imaging system. S. Kiyomiya, H. Nakanishi, H. Uchida, A. Tsuji, S. Nishiyama, M. Futatsubashi, H. Tsukada, N. S. Ishioka, S. Watanabe, T. Ito, C. Mizuniwa, A. Osa, S. Matsuhashi, S. Hashimoto, T. Sekine, S. Mori. Plant Physiology 125: 1743-1753, 2001

Light activates H215O flow in rice: Detailed monitoring using a positron-emitting tracer imaging system (PETIS). S. Kiyomiya, H. Nakanishi, H. Uchida, S. Nishiyama, H. Tsukada, N. S. Ishioka, S. Watanabe, A. Osa, C. Mizuniwa, T. Ito, S. Matsuhashi, S. Hashimoto, T. Sekine, A. Tsuji, S. Mori. Physiologia Plantarum 113: 359-367, 2001

Ion chromatographic analysis of selected free amino acids and cations to investigate the change of nitrogen metabolism by herbicide stress in soybean (Glycine max). M. H. Jia, N. Keutgen, S. Matsuhashi, C. Mitzuniwa, T. Ito, T. Fujimura, S. Hashimoto. Journal of Agricultural and Food Chemistry 49: 276-280, 2001

Vanadium uptake and an effect of vanadium treatment on 18F-labeled water movement in a cowpea plant by positron emitting tracer imaging system (PETIS). J. Furukawa, H. Yokota, K. Tanoi, S. Ueoka, S. Matsuhashi, N. S. Ishioka, S. Watanabe, H. Uchida, A. Tsuji, T. Ito, T. Mizuniwa, A. Osa, T. Sekine, S. Hashimoto, T. M. Nakanishi. Journal of Radioanalytical and Nuclear Chemistry 249: 495-498, 2001

Real-time [11C]methionine translocation in barley in relation to mugineic acid phytosiderophore biosynthesis. N. Bughio, H. Nakanishi, S. Kiyomiya, S. Matsuhashi, N. S. Ishioka, S. Watanabe, H. Uchida, A. Tsuji, A. Osa, T. Kume, S. Hashimoto, T. Sekine, S. Mori. Planta 213: 708-715, 2001

2000

Visualization of 15O-water flow in tomato and rice in the light and dark using a positron-emitting tracer imaging system (PETIS). S. Mori, S. Kiyomiya, H. Nakanishi, N. S. Ishioka, S. Watanabe, A. Osa, S. Matsuhashi, S. Hashimoto, T. Sekine, H. Uchida, S. Nishiyama, H. Tsukada, A. Tsuji. Soil Science and Plant Nutrition 46: 975-979, 2000

1999

Production of radioactive endovascular stents by implantation of 133Xe ions. S. Watanabe, A. Osa, T. Sekine, N. S. Ishioka, M. Koizumi, T. Kojima, A. Hasegawa, M. Yoshii, E. Okamoto, K. Aoyagi, A. Miyajima, R. Nagai. Applied Radiation and Isotopes 51: 197-202, 1999

T. Sekine, H. Matsuoka. Production and utilization of radioisotopes. Proc. 3rd workshop on neutron science project -- Science and Technology in the 21st century opened by intense spallation neutron source--; 207, 1999

Analysis of nitrate absorption and transport in non-nodulated and nodulated soybean plants with 13NO3-and 15NO3-. T. Sato, N. Ohtake, T. Ohyama, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, H. Uchida, A. Tsuji, S. Matsuhashi. Radioisotopes 48: 450-458, 1999

Visualizing real time [11C]methionine translocation in Fe-sufficient and Fe-deficient barley using a Positron Emitting Tracer Imaging System (PETIS). H. Nakanishi, N. Bughio, S. Matsuhashi, N. S. Ishioka, H. Uchida, A. Tsuji, A. Osa, T. Sekine, T. Kume, S. Mori. Journal of Experimental Botany 50: 637-643, 1999

Mössbauer spectroscopy of 133Cs following the decay of 133Xe atoms implanted in metals. H. Muramatsu, H. Ishii, E. Tanaka, M. Misawa, H. Ito, T. Miura, S. Muto, M. Koizumi, A. Osa, T. Sekine, M. Yanaga. Journal of Radioanalytical and Nuclear Chemistry 239: 251-255, 1999

13N-nitrate uptake sites and rhizobium-infectible region in a single root of common bean and soybean. H. Matsunami, Y. Arima, K. Watanabe, N. S. Ishioka, S. Watanabe, A. Osa, T. Sekine, H. Uchida, A. Tsuji, S. Matsuhashi, T. Itoh, T. Kume. Soil Science and Plant Nutrition 45: 955-962, 1999

The accelerator production of molybdenum-99. R. M. Lambrecht, T. Sekine, H. V. Ruiz. Production technologies for molybdenum-99 and technetium-99m. IAEA-TECDOC-1065, 75. 1999

Alice predictions on the accelerator production of molybdenum-99. R. M. Lambrecht, T. Sekine, H. V. Ruiz. Applied Radiation and Isotopes 51: 177-182, 1999

Comments on the cross sections of 186Re in the 186W(p, n) and 186W(d, 2n) reactions in connection to the paper given by Z. H. Zhu et al. and correction of the calculated yields of 186Re in the 186W(p, n) reaction. N. S. Ishioka, T. Sekine, R. M. Lambrecht. Journal of Radioanalytical and Nuclear Chemistry 241: 383-383, 1999

Production of positron emitters and application of their labeled compounds to plant studies. N. S. Ishioka, H. Matsuoka, S. Watanabe, A. Osa, M. Koizumi, T. Kume, S. Matsuhashi, T. Fujimura, A. Tsuji, H. Uchida, T. Sekine. Journal of Radioanalytical and Nuclear Chemistry 239: 417-421, 1999

1998

Calibration and interpretation of M ssbauer isomer shift of the 81-keV transition in 133Cs. H. Muramatsu, E. Tanaka, H. Ishii, H. Ito, M. Misawa, T. Miura, Y. Fujita, K. Omata, S. Muto, M. Koizumi, A. Osa, T. Sekine, M. Yanaga, K. Endo, H. Nakahara, M. Fujioka. Physical Review B 58: 11313, 1998

A simple retardation system for low-energy implantation of mass-separated radioactive ions. H. Muramatsu, H. Ishii, E. Tanaka, A. Osa, M. Koizumi, T. Sekine, T. Miura, M. Fujioka. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms 134: 126-135, 1998

N. S. Ishioka, T. Sekine, H. Matsuoka, S. Watanabe, A. Osa, M. Koizumi, T. Kume, S. Matsuhashi, T. Fujimura, H. Uchida, A. Tsuji, L. X. Tham, V. H. Dang. Application of positron emitters to studies on plants. Proc. of 1997 Workshop on the Utilization of Research Reactors; 349, 1998

著書・総説・解説

原子力教科書放射線利用「医療における放射線利用」松橋信平、石岡典子、(株)オーム社、(2011年出版)

内分泌画像検査・診断マニュアル「褐色細胞腫の新しいPET診断薬:76Br-MBBG」石岡典子、渡邉茂樹、花岡宏史、(株)診断と治療社(2011年出版)

がん診断・治療に向けた新しいRI標識薬剤の開発.渡辺茂樹,石岡典子放射線と産業129,27-31,2011

76Br-MBBGを用いた褐色細胞腫のPETイメージング.渡辺茂樹,石岡典子,Isotope News 680:2-6,2010

イオンビームによる有用RIの生成とライフサイエンスへの応用.石岡典子.Isotope News 673:14-18,2010

日本のRI研究開発の現状.石岡典子.原子力eye 55(7):20-23,2009

生命科学分野で役立つポジトロン放出核種を用いた非侵襲的計測技術,石岡典子,藤巻秀.放射線と産業,124,21-26(2009).

土壌中からのカドミウムの除去技術(ファイトレメディエーション)の実用化を目指した研究におけるポジトロンイメージング技術の貢献.中村進一,茅野充男,藤巻秀,鈴井伸郎,石岡典子,河地有木,松橋信平.放射線と産業117:9-14,2008

AVFサイクロトロンによる植物研究用ポジトロン放出核種標識化合物の製造.石岡典子.放射線と産業80:11-15,1998

 

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