Protein Functional Analysis Team

​Bio organisms have been born and evolved over 4 billion years. The bio molecules basically comprise the bio organisms, and have acquired remarkable functions in a long evolutionary time. Proteins are molecules that play pivotal roles in the biology. Quantum effects are one of the key factors realizing the remarkable protein functions. We believe that exploring the quantum effects of proteins and deepening their understanding will lead to ideas for producing novel and functional molecules. We aim to develop such new molecules that are useful in our lives.

Team Leader, Motoyasu Adachi

Members

​Team Leader, Motoyasu Adachi

Senior Principal Researcher, Shigeki Arai

Principal Researcher, Takatoshi Fujita

Senior Staff, Hiroshi Murakami

Postdoctoral Fellow, Misa Nozaki

Recent Publications​

1. Nonthermal Effect of Microwave Irradiation on the Molecular Level: Emergence of Coherent Subterahertz Vibrations of Hydration Water in Reverse Micelles. Murakami H. J. Phys. Chem. Lett. 2536-2540 (2025).
2. Rational Design and Engineering of Conducting Polymers for Chemical Enhancement in Raman Scattering. Zhang H., Dong J.Y., Tang X., Kishimoto N., Deng Y., Zhang H., Yu X., Nakagawa Y., Zhang S.T., Kagotani Y., Adachi M., Zhou Y., Kitahama Y., Marumi M., Kacenauskaite L., Pancorbo P.M., Shigeta Y., Iwasaki A., Ma Y., Xiao T.H., Goda K. Adv. Opt. Mater. (2025).
3. Anomalously Large Heat Generation of Hydration Water under Microwave Irradiation. Murakami H. J. Phys. Chem. B. 128(16), 3898-3903 (2024) .
4. Electronic structures of blue copper centers of amicyanin and azurin in solution state. Izumi Y., Ugalino R., Miyawaki J., Shibazaki C., Adachi M., Kurahashi N., Kiuchi H., Harada Y., Fujii K. Dalton Trans. 54 (2024).
5. Possibility of two-dimensional ordering of cryptochrome 4a from European robin. Arai S., Kobayashi R., Adachi M., Koji K., Hirokazu M., Biochem. Biophys. Res. Commun. 737, 150513 (2024).
6. Beat-frequency-resolved two-dimensional electronic spectroscopy: disentangling vibrational coherences in artificial fluorescent proteins with sub-10-fs visible laser pulses. Tsubouchi M., Ishii N, Kagotani Y., Shimizu R, Fujita T., Adachi M., Itakura R. Opt. Express, 31(4), 6890-6906 (2023).
7. Exciton quantum dynamics in the molecular logic gates for quantum computing Yonetani Y.  Chemical Physics, 570, 111860, (2023).
8. Unusual microwave heating of water in reverse micellar solution. Murakami H.  Sci. Rep., 13(1), 5025 (2023).
9. Fibrillization Process of Human Amyloid-Beta Protein (1-40) under a Molecular Crowding Environment Mimicking the Interior of Living Cells Using Cell Debris. Hirai M,  Arai S, Iwase H. Molecules, 28(18), 6555 (2023).
10. Ab Initio Study of Charge Separation Dynamics and Pump-Probe Spectroscopy in the P3HT/PCBM Blend, Fujita T. and Hoshi T. J. Phys. Chem. B, 127(35), 7615-7623 (2023).
11. Deciphering the Potential of Multidimensional Carbon Materials for Surface-Enhanced Raman Spectroscopy through Density Functional Theory. Tang X, Kishimoto N, Kitahama Y, You TT, Adachi M, Shigeta Y, Tanaka S, Xiao TH, Goda K. J. Phys. Chem. Lett. 14(45), 10208-10218 (2023).