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Institute for Quantum Medical Science

Applied MRI Research Group

Update:2025年6月30日更新
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​Applied MRI Research and Diagnostic Imaging 

We develop new techniques for MRI and other imaging modalities, and then deploy them in clinical applications in collaboration with specialist researchers. In parallel with this, we also seek evidence for the physiological sources of signals.We also undertake safety assessments and quality control for the techniques in accordance with international guidelines.

MRI biomarker

ADC

AMR QR​ Applied MRI Research

Member

Obata Takayuki Group reader

Obata Takayuki Group reader

  • Obata Takayuki Group reader
  • Tachibana Yasuhiko Senior Principal Researcher
  • Ikoma Yoko Principal Researcher
  • Miyata Mari Senior Researcher
  • Kershaw Jeffrey Senior Researcher
  • Sano Hiromi Senior Researcher
  • Sahara Yasuka
  • Ishii Akino Technical Staff
  • Kamada Hiroko Technical Staff
  • Higuchi Kaomi Assistant

Concurrent member

  • Umehara Kensuke Senior Researcher
  • Ota Junko Senior Researcher
  • Omatsu Tokuhiko Section Manager
  • Takuwa Hiroyuki Senior Principal Researcher
  • Takahashi Manami Postdoctoral Fellow
  • Takakusagi Yoichi Group reader
  • Takado Yuhei Principal Researcher
  • Yahata Noriaki Senior Researcher
  • Majima Kei Researcher
  • Yoshioka Naho Staff

Selected Publications

  1. Ohmatsu K.,Omatsu T.,Okonogi N.,Ikoma Y.,Murata K.,Kishimoto R.,Obata T.,Yamada S.,Karasawa K.:Changes in Intratumor Blood Flow After Carbon-Ion Radiation Therapy for Early-Stage Breast Cancer.Int J Part Ther,12,100018(2024)
  2. Kameda H.,Kinota N.,Kato D.,Fujii T.,Harada T.,Komaki Y.,Sugimori H.,Onodera T.,Tomiyasu M.,Obata T.,Kudo K.: Magnetic Resonance Water Tracer Imaging Using 17 O-Labeled Water.Invest Radiol,59(1),92-103,(2024)
  3. Kurita K.,Obata T.,Sutoh C.,Matsuzawa D.,Yoshinaga N.,Kershaw J.,Chhatkuli RB.,Ota J.,Shimizu E.,Hirano Y.: Individual cognitive therapy reduces frontal-thalamic resting-state functional connectivity in social anxiety disorder. Front Psychiatry,14,1233564.(2023)
  4. Imaizumi A.,Hirayama R.,Ikoma Y.,Nitta N.,Obata T.,Hasegawa S.:Neon ion ((20) Ne(10)(+)) charged particle beams manipulate rapid tumor reoxygenation in syngeneic mouse models.Cancer Sci,115(1),227-236,(2024)
  5. Tachibana Y.,Otsuka Y.,Nozaki H.,Kamagata K.,Mori S.,Saito Y.,Aoki S.:Noise reduction by multiple path neural network using Attention mechanisms with an emphasis on robustness against Errors:A pilot study on brain Diffusion-Weighted images.Phys Med,116,103176,(2023)
  6. Tomiyasu M.,Sahara Y.,Mitsui E.,Tsuchiya H.,Maeda T.,Tomoyori N.,Kawashima M.,Nogawa T.,Kishimoto R.,Takado Y.,Higashi T.,Mizota A.,Kudo K.,Obata T.:Intraocular Water Movement Visualization Using (1) H-MRI With Eye Drops of O-17-Labeled Saline: First-in-Human Study.J Magn Reson Imaging,57(3),845-853,(2023)
  7. Tsuchiya H.,Tachibana Y.,Kishimoto R.,Omatsu T.,Hotta E.,Tanimoto K.,Wakatsuki M.,Obata T.,Tsuji H.:Dual-Energy Computed Tomography-Based Iodine Concentration Estimation for Evaluating Choroidal Malignant Melanoma Response to Treatment:Optimization and Primary Validation.Diagnostics(Basel),12(11),2692,(2022)
  8. Ota J.,Umehara K.,Kershaw J.,Kishimoto R.,Hirano Y.,Tachibana Y.,Ohba H.,Obata T.:Super-resolution generative adversarial networks with static T2*WI-based subject-specific learning to improve spatial difference sensitivity in fMRI activation.Scientific Reports,12(1),10319,(2022)
  9. Kishimoto R.,Suga M.,Usumura M.,Iijima H.,Yoshida M.,Hachiya H.,Shiina T.,Yamakawa M.,Konno K.,Obata T.,Yamaguchi T.:Shear wave speed measurement bias in a viscoelastic phantom across six ultrasound elastography systems:a comparative study with transient elastography and magnetic resonance elastography.J Med Ultrason(2001),49(2),143–152,(2022)
  10. Kershaw J.,Obata T.:Oscillating-gradient spin-echo diffusion-weighted imaging (OGSE-DWI) with a limited number of oscillations:I.Signal equation.J Magn Reson,326,106962,(2021)
  11. Ikoma Y.,Kishimoto R.,Tachibana Y.,Omatsu T.,Kasuya G.,Makishima H.,Higashi T.,Obata T.,Tsuji H.:Reference region extraction by clustering for the pharmacokinetic analysis of dynamic contrast-enhanced MRI in prostate cancer.Magn Reson Imaging,66,185-192(2020)