Technology developments on cyclotron accelerators
Two cyclotrons are used for production of radioactive isotopes (RI) and for basic research in the fields of physics and biology. In RI production, in addition to RI for molecular imaging used in the diagnosis of cancer and dementia, RI for targeted radionuclide therapy is produced for drug discovery research. A stable supply of high-quality, high-intensity beams is required to produce a various kinds and a sufficient amount of RI. Therefore, we are conducting research such as the development of techniques for increasing the intensity of beams, irradiation of high-intensity beams, and diagnostic techniques.
Left: Two cyclotron accelerators, Right: Target systems for RI production
Member
Wakui Takashi Section Manager
- Hojo Satoru Senior Principal Researcher
- Sugiura Akinori Principal Researcher
Concurrent member
- Katagiri Ken Section Manager
- Muramatsu Masayuki Principal Researcher
Selected Publications
- Hojo S., Wakui T., Sugiura A., Muramatsu M., Katagiri K., Okada T., Kamiya T., Iwata Y., Shirai T.: Status report of NIRS-930 and HM-18 cyclotrons at QST-iQMS. Proceedings of the 21th Annual Meeting of Particle Accelerator Society of Japan, 1219 (2024).
- Muramatsu M., Wakui T., Hojo S., Sugiura A., Okada T., Kamiya T.: Restoration of compact ECR ion source for NIRS-930 cyclotron at QST-iQMS. Proceedings of the 21th Annual Meeting of Particle Accelerator Society of Japan, 518 (2024).
- Hojo S., Wakui T., Sugiura A., Muramatsu M., Okada T., Kamiya T., Shirai T.: Status report of NIRS-930 and HM-18 cyclotrons at QST-iQMS. Proceedings of the 20th Annual Meeting of Particle Accelerator Society of Japan, 1098 (2023).
- Kusumoto T., Inaniwa T., Mizushima K., Sato S., Hojo S., Kitamura H., Konishi T., Kodaira S.: Radiation chemical yields of 7-hydroxy-coumarin-3-carboxylic acid for proton- and carbon-ion beams at ultra-high dose rates: potential roles in FLASH effects. Radiation Research 198, 255 (2022).
- Sugiura A., Wakui T., Hojo S., Muramatsu M., Okada T., Kamiya T., Yamaguchi M., Shirai T.: Status report of NIRS-930 and HM-18 cyclotrons at QST-iQMS. Proceedings of the 19th Annual Meeting of Particle Accelerator Society of Japan, 1155 (2022).
- Ohsawa D., Hirayama Y., Kobayashi A., Kusumoto T., Kitamura H., Hojo S., Kodaira S., Konishi T.: DNA strand break induction of aqueous plasmid DNA exposed to 30 MeV protons at ultra-high dose rate. Journal of Radiation Research 63, 255 (2022).
- Muramatsu M., Kamiya T., Okada T., Katagiri K., Sugiura A., Hojo. S., Wakui T.: Optimization of puller position at compact ECR ion source. Proceedings of the 18th Annual Meeting of Particle Accelerator Society of Japan, 798 (2021).
- Katagiri K., Kawamura K, Wakui T, Muramatsu M, Hayashizaki N.: Design study of compact EBIS for light-ion production using low-energy hollow electron beams. Nuclear Instruments and Method A987, 164837 (2020).
- Kusumoto T., Kitamura H., Hojo S., Konishi T., Kodaira S.: Significant changes in yields of 7-hydroxy-coumarin-3-carboxylic acid produced under FLASH radiotherapy conditions. RSC Advances 10, 38709 (2020).
- Katagiri K., Wakui T., Hojo S., Boytsov A. Y., Donets E.D., Donets E.E., Ramzdorf A. Y., Noda A., Shirai T., Noda K.: Ion-production efficiency of a singly charged ion source developed toward a 11C irradiation facility for cancer therapy. Review of Scientific Instruments 90, 053303 (2019).