Research Overview
Project “Medical Radioisotope Applications” is advancing developments of basic techniques for the production of novel radioisotopes (radionuclides) promising to applications in life science, especially targeted radionuclide therapy (TRT), as a part of “Atoms for Peace”. Radioisotopes with appropriate chemical and physical properties (types of radiation and their energies, half-lives, and so on) should be selected for their clinical use. We have been therefore working on projects by utilizing quantum beams generated by the AVF930 cyclotron in TIARA and Tandem Accelerator Facility in Japan Atomic Energy Agency (JAEA)-Tokai, as follows;
- Novel diagnostic and therapeutic radioisotope productions
- Novel isolation processes from irradiated targets
- Novel labeling methods to biomolecules via labelling moieties and bifunctional chelators
- Evaluation of novel radiolabeled compounds for TRT
- Dosimetry for TRT
Radioisotopes produced in TIARA (211At, 64Cu) has been supplied to universities and institutes all over Japan through Supply Platform of Short-lived Radioisotopes.
Contact
Project Leader
Noriko S. ISHIOKA, Ph.D.
Project "Medical Radioisotope Application"
Department of Quantum-Applied Biosciences
Takasaki Institute of Advanced Quantum Science
Foundational Quantum Technology Research Directorate
National Institutes for Quantum Science and Technology
Watanuki 1233, Takasaki, Gunma 370-1292, Japan